hrp0086p1-p252 | Diabetes P1 | ESPE2016

Clinical Case of a 10-year-old Girl with Papillomatosis Due to Severe Insulin Resistance Type A

Orlova Elizaveta , Makazan Nadezhda , Kareva Maria , Mayorov Alexandr , Koksharova Ekaterina , Peterkova Valentina

Background: Severe insulin resistant (IR) type A is a rare inherited disorder characterized by glucose metabolism disturbances without obesity, acanthosis nigricans and hyperandrogenia due to INSR defects.Case report: A 10-year-old girl was admitted because of skin papillomatosis and hyperpigmentations since her 7 years. She had early puberty with pubarche at 8 years and telarche at 9 years. Examination revealed normal height and weight (SDS BMI...